Ideally patients should consult their personal physicians with regard to the ideal dosage, as it depends on a wide range of factors which can differ from one person to another. You must not make any adjustments to the dose that you have been prescribed without your physician’s approval. The average dose of Nexium consists of:

- Nexium 20-40mg in the case of adults; this dose should be taken in once per day (this prevents GERD);
- Nexium 20 mg in the case of adults who are suffering from GERD (this dose should be taken in once every day);
- Nexium 40mg (a single time each day) in the case of adult patients who are treating ulcers.